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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5539126
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Probe: MTF#181
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:5318: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: ureteric tip Absent GUDMAP:5318
TS23: ureteric trunk Absent GUDMAP:5318
TS23: renal interstitium Absent GUDMAP:5318
TS23: cap mesenchyme Present GUDMAP:5318
TS23: early tubule Absent GUDMAP:5318
TS23: late tubule Absent GUDMAP:5318
TS23: renal vasculature Absent GUDMAP:5318
TS23: ureter Absent GUDMAP:5318
TS23: urethra of male Present GUDMAP:5318
TS23: bladder Absent GUDMAP:5318
TS23: testis Absent GUDMAP:5318
TS23: male associated reproductive structure Absent GUDMAP:5318
Specimen GUDMAP:7731: postnatal day 0 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: cap mesenchyme Present GUDMAP:7731
Specimen GUDMAP:11826: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: bladder Present GUDMAP:11826
TS23: urothelium of bladder Present GUDMAP:11826
TS23: urothelium of bladder fundus Present GUDMAP:11826
TS23: urothelium of bladder trigone Present GUDMAP:11826
TS23: urothelium of ventral bladder neck Present GUDMAP:11826
TS23: urethra of male Present GUDMAP:11826
TS23: pelvic urethra of male Present GUDMAP:11826 Strong expression in signaling center
TS23: epithelium of pelvic urethra of male Present GUDMAP:11826 Strong expression ventral, weak expression dorsal and lateral.
TS23: mesenchymal layer of pelvic urethra of male Present GUDMAP:11826
Specimen GUDMAP:12795: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: ureteric tip Absent GUDMAP:12795
TS23: ureteric trunk Absent GUDMAP:12795
TS23: renal interstitium Absent GUDMAP:12795
TS23: cap mesenchyme Present GUDMAP:12795
TS23: early tubule Absent GUDMAP:12795
TS23: late tubule Absent GUDMAP:12795
TS23: renal vasculature Absent GUDMAP:12795
TS23: ureter Absent GUDMAP:12795
TS23: urethra of female Present GUDMAP:12795
TS23: bladder Absent GUDMAP:12795
TS23: ovary Absent GUDMAP:12795
TS23: female associated reproductive structure Absent GUDMAP:12795
Specimen GUDMAP:12796: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: ureteric tip Absent GUDMAP:12796
TS23: ureteric trunk Absent GUDMAP:12796
TS23: renal interstitium Absent GUDMAP:12796
TS23: cap mesenchyme Present GUDMAP:12796
TS23: early tubule Absent GUDMAP:12796
TS23: late tubule Absent GUDMAP:12796
TS23: renal vasculature Absent GUDMAP:12796
TS23: ureter Absent GUDMAP:12796
TS23: urethra of male Present GUDMAP:12796
TS23: bladder Absent GUDMAP:12796
TS23: testis Absent GUDMAP:12796
TS23: male associated reproductive structure Absent GUDMAP:12796
Specimen GUDMAP:13965: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:13965
TS23: metanephros Present GUDMAP:13965
TS23: nephrogenic zone Present GUDMAP:13965
TS23: cap mesenchyme Present GUDMAP:13965
TS23: nephrogenic interstitium Present Regionally restricted GUDMAP:13965
TS23: pretubular aggregate Ambiguous GUDMAP:13965 Possible expression in pretubular aggregates, however these structures are difficult to identify.
TS23: ureteric tip Absent GUDMAP:13965
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:13965
TS23: renal cortex Absent GUDMAP:13965
TS23: renal medulla Absent GUDMAP:13965
TS23: renal pelvis Absent GUDMAP:13965
TS23: ureter Absent GUDMAP:13965
TS23: renal vesicle Absent GUDMAP:13965
TS23: comma-shaped body Absent GUDMAP:13965
TS23: s-shaped body Absent GUDMAP:13965
TS23: capillary loop renal corpuscle Absent GUDMAP:13965
TS23: maturing renal corpuscle Absent GUDMAP:13965
TS23: cortical renal tubule Absent GUDMAP:13965
TS23: cortical collecting duct Absent GUDMAP:13965
TS23: renal cortical interstitium Absent GUDMAP:13965
TS23: renal cortical vasculature Absent GUDMAP:13965
TS23: immature loop of Henle Absent GUDMAP:13965
TS23: medullary collecting duct Absent GUDMAP:13965
TS23: renal medullary interstitium Absent GUDMAP:13965
TS23: renal medullary vasculature Absent GUDMAP:13965
TS23: pelvic urothelial lining Absent GUDMAP:13965
TS23: pelvic smooth muscle Absent GUDMAP:13965
TS23: perihilar interstitium Absent GUDMAP:13965
Specimen GUDMAP:14085: postnatal day 0 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: urinary system Present GUDMAP:14085
TS27: metanephros Present GUDMAP:14085
TS27: nephrogenic zone Present GUDMAP:14085
TS27: renal cortex Present GUDMAP:14085
TS27: pretubular aggregate Present GUDMAP:14085
TS27: renal vesicle Present GUDMAP:14085
TS27: cap mesenchyme Present GUDMAP:14085
TS27: nephrogenic interstitium Absent GUDMAP:14085
TS27: ureteric tip Absent GUDMAP:14085
TS27: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14085
TS27: comma-shaped body Absent GUDMAP:14085
TS27: s-shaped body Absent GUDMAP:14085
TS27: capillary loop renal corpuscle Absent GUDMAP:14085
TS27: maturing renal corpuscle Absent GUDMAP:14085
TS27: mature renal corpuscle Absent GUDMAP:14085
TS27: cortical renal tubule Absent GUDMAP:14085
TS27: cortical collecting duct Absent GUDMAP:14085
TS27: renal cortical interstitium Absent GUDMAP:14085
TS27: renal cortical vasculature Absent GUDMAP:14085
TS27: renal medulla Absent GUDMAP:14085
TS27: renal pelvis Absent GUDMAP:14085
Specimen GUDMAP:14086: postnatal day 2 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: urinary system Present GUDMAP:14086
TS27: metanephros Present GUDMAP:14086
TS27: nephrogenic zone Present GUDMAP:14086
TS27: renal cortex Present GUDMAP:14086
TS27: renal vesicle Present GUDMAP:14086
TS27: cap mesenchyme Ambiguous GUDMAP:14086
TS27: nephrogenic interstitium Absent GUDMAP:14086
TS27: ureteric tip Absent GUDMAP:14086
TS27: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14086
TS27: s-shaped body Present GUDMAP:14086
TS27: capillary loop renal corpuscle Absent GUDMAP:14086
TS27: maturing renal corpuscle Absent GUDMAP:14086
TS27: mature renal corpuscle Absent GUDMAP:14086
TS27: cortical renal tubule Absent GUDMAP:14086
TS27: cortical collecting duct Absent GUDMAP:14086
TS27: renal cortical interstitium Absent GUDMAP:14086
TS27: renal cortical vasculature Absent GUDMAP:14086
TS27: renal medulla Absent GUDMAP:14086
TS27: renal pelvis Absent GUDMAP:14086
Specimen GUDMAP:14087: postnatal day 4 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: metanephros Absent GUDMAP:14087
TS27: nephrogenic zone Absent GUDMAP:14087 No cap mesenchyme present at P4 therefore no Six2 expression in this structure within the nephrogenic zone at P4.
TS27: renal cortex Absent GUDMAP:14087
TS27: renal medulla Absent GUDMAP:14087
TS27: renal pelvis Absent GUDMAP:14087
Specimen GUDMAP:14169: postnatal day 6 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: metanephros Absent GUDMAP:14169
TS28: nephrogenic zone Absent GUDMAP:14169
TS28: renal cortex Absent GUDMAP:14169
TS28: renal medulla Absent GUDMAP:14169
TS28: nephrogenic interstitium Absent GUDMAP:14169
TS28: cap mesenchyme Absent GUDMAP:14169
TS28: pretubular aggregate Absent GUDMAP:14169
TS28: ureteric tip Absent GUDMAP:14169
TS28: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14169
Specimen GUDMAP:14170: embryonic day 17.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS25: metanephros Present GUDMAP:14170
TS25: nephrogenic zone Present GUDMAP:14170
TS25: cap mesenchyme Present GUDMAP:14170
TS25: nephrogenic interstitium Absent GUDMAP:14170
TS25: ureteric tip Absent GUDMAP:14170
TS25: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14170
TS25: renal cortex Absent GUDMAP:14170
TS25: renal medulla Absent GUDMAP:14170
TS25: renal pelvis Absent GUDMAP:14170
TS25: ureter Absent GUDMAP:14170
Specimen GUDMAP:20700: embryonic day 15.0 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: pelvic urethra of female Present GUDMAP:20700
TS23: mesenchymal layer of ventral pelvic urethra of female Present GUDMAP:20700
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory