Gene Expression Data
Assay Details
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Assay
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Reference:
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J:22369
Tojo H, et al., Targeted disruption of the neurotrophin-3 gene with lacZ induces loss of trkC-positive neurons in sensory ganglia but not in spinal cords. Brain Res. 1995 Jan 16;669(2):163-75
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5525081
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Gene symbol:
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Ntf3
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Gene name:
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neurotrophin 3
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
2B:
(close  )
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Genetic Background:
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involves: C57BL/6 * DBA/2 * ICR
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Mutant Allele(s):
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Ntf3tm1Tojo/Ntf3tm1Tojo
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Age:
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embryonic day 14.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Glutaraldehyde
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Note:
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Fixative was 1% glutaraldehyde.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: peripheral nervous system |
Present |
Regionally restricted |
2B
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Expression is in peripheral target tissues of sensory and motor nerves.
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| TS22: genital tubercle |
Present |
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2B
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Expression is in peripheral target tissues of sensory nerves.
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| TS22: outer ear |
Present |
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2B
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Expression is in peripheral target tissues of sensory nerves.
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| TS22: eye |
Present |
Regionally restricted |
2B
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Expression is in peripheral target tissues of sensory nerves at the rim of the eyes.
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| TS22: skin |
Strong |
Regionally restricted |
2B
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Expression is in peripheral target tissues of sensory nerves in the regions around vibrissae.
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| TS22: limb |
Weak |
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2B
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Expression is in peripheral target tissues of sensory nerves.
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Specimen
3A:
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2 * ICR
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Mutant Allele(s):
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Ntf3tm1Tojo/Ntf3tm1Tojo
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Age:
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embryonic day 17.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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Specimen
3B:
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2 * ICR
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Mutant Allele(s):
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Ntf3tm1Tojo/Ntf3tm1Tojo
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Age:
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embryonic day 17.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: trigeminal ganglion |
Strong |
Single cells |
3B
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Expression is in a limited number of neurons.
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Specimen
3C:
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2 * ICR
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Mutant Allele(s):
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Ntf3tm1Tojo/Ntf3tm1Tojo
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Age:
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embryonic day 17.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: skin |
Strong |
Regionally restricted |
3C
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In the whisker pad expression is in the region slightly external from the hair follicles.
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Specimen
3D:
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2 * ICR
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Mutant Allele(s):
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Ntf3tm1Tojo/Ntf3tm1Tojo
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Age:
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embryonic day 17.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: iris |
Present |
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3D
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Specimen
3E:
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2 * ICR
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Mutant Allele(s):
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Ntf3tm1Tojo/Ntf3tm1Tojo
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Age:
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embryonic day 17.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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Specimen
3F:
(close )
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Genetic Background:
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involves: C57BL/6 * DBA/2 * ICR
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Mutant Allele(s):
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Ntf3tm1Tojo/Ntf3tm1Tojo
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Age:
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embryonic day 17.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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)
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