Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bcrtm1(BCR/ABL)Tsr
Name:	BCR activator of RhoGEF and GTPase; targeted mutation 1, Theodora S Ross
MGI ID:	MGI:5524984
Synonyms:	BcrLSL-B/A, BcrLSL-BCR/ABL
Gene:	Bcr  Location: Chr10:74896424-75020753 bp, + strand  Genetic Position: Chr10, 38.49 cM
Alliance:	Bcrtm1(BCR/ABL)Tsr page

Germline Transmission:	Earliest citation of germline transmission: J:203111
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted Mutation:    Insertion   Mutation details: Human BCR/ABL p210-IRES-EGFP cDNA and an Frt-flanked neomycin cassette were introduced to exon 1 of the mouse Bcr gene downstream of a loxP-flanked Stop cassette via homologous recombination. (J:203111)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Bcr Mutation:	51 strains or lines available

Original:	J:203111 Foley SB, et al., Expression of BCR/ABL p210 from a knockin allele enhances bone marrow engraftment without inducing neoplasia. Cell Rep. 2013 Oct 17;5(1):51-60
All:	3 reference(s)