Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Bscl2tm1Geno
Name:	BSCL2 lipid droplet biogenesis associated, seipin; targeted mutation 1, Genoway
MGI ID:	MGI:5519934
Gene:	Bscl2  Location: Chr19:8814831-8826047 bp, + strand  Genetic Position: Chr19, 5.76 cM
Alliance:	Bscl2tm1Geno page

Germline Transmission:	Earliest citation of germline transmission: J:200947
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Exons 4 through 6 were replaced with a neomycin resistance cassette. (J:200947)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

9 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bscl2 Mutation:	33 strains or lines available

Original:	J:200947 Prieur X, et al., Thiazolidinediones partially reverse the metabolic disturbances observed in Bscl2/seipin-deficient mice. Diabetologia. 2013 Aug;56(8):1813-25
All:	5 reference(s)