Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Arid5atm1Rnis
Name:	AT-rich interaction domain 5A; targeted mutation 1, Riko Nishimura
MGI ID:	MGI:5519212
Gene:	Arid5a  Location: Chr1:36346814-36363110 bp, + strand  Genetic Position: Chr1, 15.2 cM
Alliance:	Arid5atm1Rnis page

Germline Transmission:	Earliest citation of germline transmission: J:197418
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A floxed neomycin selection cassette replaced the major part of the DNA binding domain. (J:197418)

Generation of the Arid5atm1Rnis allele

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Arid5a Mutation:	31 strains or lines available

Original:	J:197418 Masuda K, et al., Arid5a controls IL-6 mRNA stability, which contributes to elevation of IL-6 level in vivo. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9409-14
All:	6 reference(s)