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Piptm1Myal
Targeted Allele Detail
Summary
Symbol: Piptm1Myal
Name: prolactin induced protein; targeted mutation 1, Yvonne Myal
MGI ID: MGI:5516489
Synonyms: mSMGP
Gene: Pip  Location: Chr6:41824483-41828999 bp, + strand  Genetic Position: Chr6, 20.05 cM, cytoband B2
Alliance: Piptm1Myal page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:202016
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exon 2. Western blot analysis confirmed the absence of protein expression in the saliva and tears. (J:202016)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pip Mutation:  16 strains or lines available
References
Original:  J:202016 Blanchard A, et al., Generation and initial characterization of the prolactin-inducible protein (PIP) null mouse: accompanying global changes in gene expression in the submandibular gland. Can J Physiol Pharmacol. 2009 Oct;87(10):859-72
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory