Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Pgk1-Ccnb1/EGFP)1Aklo
Name:	transgene insertion 1, Agnes Klochendler
MGI ID:	MGI:5515374
Synonyms:	CycB1-GFP
Transgene:	Tg(Pgk1-Ccnb1/EGFP)1Aklo  Location: unknown
Alliance:	Tg(Pgk1-Ccnb1/EGFP)1Aklo page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Pgk1-Ccnb1/EGFP)1Aklo expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Ccnb1 (MGI:88302)   Mutation details: The transgene was generated via lentitransgenesis; a self-inactivating lentiviral vector was designed with 105 N-terminal residues of the Cyclin B1 (Ccnb1) gene (harboring the APC/C ubiquitination site responsible for its specific degradation in G0/G1 cells) and an enhanced green fluorescence protein (EGFP) sequence under control of a constitutive mouse phosphoglycerate kinase 1 (Pgk1) promoter. Line 1 was generated. (J:188998)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:188998 Klochendler A, et al., A transgenic mouse marking live replicating cells reveals in vivo transcriptional program of proliferation. Dev Cell. 2012 Oct 16;23(4):681-90
All:	7 reference(s)