About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:186025 Verpy E, et al., Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane. J Comp Neurol. 2011 Feb 1;519(2):194-210
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5512894
Gene symbol: Strc
Gene name: stereocilin
Antibody: anti-stereocilin
Detection system: Secondary antibody coupled to other - see notes
Results
Specimen 3a: postnatal day 22 (more )
Note: Immunogold transmission electron microscopy.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 3a Gold particles are located mainly around the tips of the stereocilia on the tallest row of outer hair cells.
Specimen 3b: postnatal day 22 (more )
Note: Immunogold transmission electron microscopy.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 3b Gold particles were found in association with the top connectors that connect adjacent stereocilia within and between rows of outer hair cells.
Specimen 3c: postnatal day 15 (more )
Note: Scanning electron micrograph; the fixative was 2.5% glutaraldehyde.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 3c Between adjacent stereocilia, especially in the middle and short rows of stereocilia, gold particles form a ring around the tip of each stereocilium in the tallest row of stereocilia of outer hair cells.
Specimen 3d: postnatal day 15 (more )
Note: Scanning electron micrograph; the fixative was 2.5% glutaraldehyde.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 3d Between adjacent stereocilia, especially in the middle and short rows of stereocilia, gold particles form a ring around the tip of each stereocilium in the tallest row of stereocilia of outer hair cells.
Specimen 3e: postnatal day 15 (more )
Note: Scanning electron micrograph; the fixative was 2.5% glutaraldehyde.
Structure Level Pattern Image Note
TS28: tectorial membrane Present Regionally restricted 3e There is a ring of gold particles surrounded the imprints produced by the tall stereocilia on the lower surface of the membrane.
Specimen 3f: postnatal day 15; Tectatm1Gpr/Tectatm1Gpr (more )
Note: Scanning electron micrograph; the fixative was 2.5% glutaraldehyde.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 3f The ring-shaped stereocilin labeling at the tips of the tallest stereocilia was not detected in this mutant, whereas labeling of stereocilia from the middle and short rows was present.
Specimen 7c: postnatal day 8 (more )
Note: Scanning electron micrograph; the fixative was 2.5% glutaraldehyde.
Structure Level Pattern Image Note
TS28: cochlea Present 7c
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory