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Gene Expression Data
Assay Details
Assay
Reference: J:186025 Verpy E, et al., Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane. J Comp Neurol. 2011 Feb 1;519(2):194-210
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5512894
Gene symbol: Strc
Gene name: stereocilin
Antibody: anti-stereocilin
Detection system: Secondary antibody coupled to other - see notes
Results
Specimen 3a: postnatal day 22 (more )
Note: Immunogold transmission electron microscopy.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 3a Gold particles are located mainly around the tips of the stereocilia on the tallest row of outer hair cells.
Specimen 3b: postnatal day 22 (more )
Note: Immunogold transmission electron microscopy.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 3b Gold particles were found in association with the top connectors that connect adjacent stereocilia within and between rows of outer hair cells.
Specimen 3c: postnatal day 15 (more )
Note: Scanning electron micrograph; the fixative was 2.5% glutaraldehyde.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 3c Between adjacent stereocilia, especially in the middle and short rows of stereocilia, gold particles form a ring around the tip of each stereocilium in the tallest row of stereocilia of outer hair cells.
Specimen 3d: postnatal day 15 (more )
Note: Scanning electron micrograph; the fixative was 2.5% glutaraldehyde.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 3d Between adjacent stereocilia, especially in the middle and short rows of stereocilia, gold particles form a ring around the tip of each stereocilium in the tallest row of stereocilia of outer hair cells.
Specimen 3e: postnatal day 15 (more )
Note: Scanning electron micrograph; the fixative was 2.5% glutaraldehyde.
Structure Level Pattern Image Note
TS28: tectorial membrane Present Regionally restricted 3e There is a ring of gold particles surrounded the imprints produced by the tall stereocilia on the lower surface of the membrane.
Specimen 3f: postnatal day 15; Tectatm1Gpr/Tectatm1Gpr (more )
Note: Scanning electron micrograph; the fixative was 2.5% glutaraldehyde.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 3f The ring-shaped stereocilin labeling at the tips of the tallest stereocilia was not detected in this mutant, whereas labeling of stereocilia from the middle and short rows was present.
Specimen 7c: postnatal day 8 (more )
Note: Scanning electron micrograph; the fixative was 2.5% glutaraldehyde.
Structure Level Pattern Image Note
TS28: cochlea Present 7c
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
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