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Gene Expression Data
Assay Details
Assay
Reference: J:174473 Benvegnu S, et al., Neurodevelopmental expression and localization of the cellular prion protein in the central nervous system of the mouse. J Comp Neurol. 2010 Jun 1;518(11):1879-91
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5510693
Gene symbol: Prnp
Gene name: prion protein
Antibody: HuM-D18
Detection system: Secondary antibody
Results
Specimen 1H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Absent 1H
Specimen 3F: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: choroid plexus Strong 3F Expression is in the epithelial cells of the choroid plexus, specifically at the apical surface of the cells toward the ventricle.
Specimen 4A: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 4A
TS28: hippocampus molecular layer Strong 4A
TS28: hippocampus stratum lacunosum Strong 4A
TS28: neocortex layer Absent 4A
Specimen 4B: postnatal day 7 (more )
Note: Double labeled: red - Prnp; green - Nefh (assay MGI:5510705).
Structure Level Pattern Image Note
TS28: bed nucleus of stria terminalis Present 4B
TS28: fimbria hippocampus Present 4B
Specimen 4C: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: bed nucleus of stria terminalis Present 4C
TS28: fimbria hippocampus Present 4C
Specimen 4D: postnatal day 7 (more )
Note: Double labeled: red - Prnp; green - Nefh (assay MGI:5510705).
Structure Level Pattern Image Note
TS28: bed nucleus of stria terminalis Present 4D
TS28: fimbria hippocampus Present 4D
Specimen 4E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: hippocampus Present Regionally restricted 4E Expression is in the fimbria.
TS26: telencephalon Present Regionally restricted 4E Expression is in the stria terminalis.
Specimen 4F: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: bed nucleus of stria terminalis Present 4F
TS27: fimbria hippocampus Present 4F
Specimen 4G: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: bed nucleus of stria terminalis Present 4G
TS28: fimbria hippocampus Present 4G
Specimen 4H: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: bed nucleus of stria terminalis Present 4H Expression progresivily increases with development.
TS28: fimbria hippocampus Present 4H Expression progresivily increases with development.
Specimen 4I: postnatal (more )
Structure Level Pattern Image Note
TS28: bed nucleus of stria terminalis Present 4I
TS28: fimbria hippocampus Present 4I
Specimen 4J: postnatal (more )
Structure Level Pattern Image Note
TS28: bed nucleus of stria terminalis Present 4J
TS28: hippocampus Present 4J
Specimen 5A,C: postnatal day 7 (more )
Note: Double labeled: red - Prnp; green - Nefh (assay MGI:5510705).
Structure Level Pattern Image Note
TS28: thalamus Present Regionally restricted 5A , 5C Expression is in the fornix.
Specimen 5D: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: thalamus Present Regionally restricted 5D Expression is in the fasciculus retroflexus.
Specimen 5E: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: thalamus Present Regionally restricted 5E Expression is in the fasciculus retroflexus.
Specimen 5F: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: thalamus Present Regionally restricted 5F Expression is in the fasciculus retroflexus.
Specimen 5G: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: thalamus Present Regionally restricted 5G Expression is in the fasciculus retroflexus.
Specimen 5I: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: thalamus Present Regionally restricted 5I Expression is in the fornix.
Specimen 5J: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: thalamus Present Regionally restricted 5J Expression is in the fornix.
Specimen 5K: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: thalamus Present Regionally restricted 5K Expression is in the fornix.
Specimen 5L: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: thalamus Present Regionally restricted 5L Expression is in the fasciculus retroflexus.
Specimen 5M: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: thalamus Present Regionally restricted 5M Expression is in the fasciculus retroflexus.
Specimen 5N: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: thalamus Present Regionally restricted 5N Expression is in the fasciculus retroflexus. There is an progressively increasing level of expression of the protein during development.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory