Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Clec4gtm1.1Fhe
Name:	C-type lectin domain family 4, member g; targeted mutation 1.1, Fuchu He
MGI ID:	MGI:5510586
Gene:	Clec4g  Location: Chr8:3757064-3770651 bp, - strand  Genetic Position: Chr8, 1.92 cM
Alliance:	Clec4gtm1.1Fhe page

Germline Transmission:	Earliest citation of germline transmission: J:200968
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region was replaced by a floxed PGK-neomycin selection cassette. The selection cassette was then removed from properly targeted mice by cre excision. Absence of transcription was confirmed by rtPCR and loss of protein by immunofluorescein staining. (J:200968)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Clec4g Mutation:	29 strains or lines available

Original:	J:200968 Tang L, et al., Liver sinusoidal endothelial cell lectin, LSECtin, negatively regulates hepatic T-cell immune response. Gastroenterology. 2009 Oct;137(4):1498-508.e1-5
All:	5 reference(s)