Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Uba6tm1Whpr
Name:	ubiquitin-like modifier activating enzyme 6; targeted mutation 1, Wade Harper
MGI ID:	MGI:5509054
Synonyms:	Uba6flox
Gene:	Uba6  Location: Chr5:86258579-86320602 bp, - strand  Genetic Position: Chr5, 43.56 cM
Alliance:	Uba6tm1Whpr page

Germline Transmission:	Earliest citation of germline transmission: J:198126
Parent Cell Line:	iTL BA1 (ES Cell)
Strain of Origin:	(C57BL/6NTac x 129S6/SvEvTac)F1

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 16. A second loxP site, followed by a FRT-flanked neomycin resistance (neo) cassette, was inserted downstream of exon 17. (J:198126)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Uba6 Mutation:	59 strains or lines available

Original:	J:198126 Lee PC, et al., Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system. Mol Cell. 2013 Apr 25;50(2):172-84
All:	4 reference(s)