Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kdm6atm1c(EUCOMM)Jae
Name:	lysine (K)-specific demethylase 6A; targeted mutation 1c, Rudolf Jaenisch
MGI ID:	MGI:5507836
Synonyms:	Utxflx
Gene:	Kdm6a  Location: ChrX:18028814-18146175 bp, + strand  Genetic Position: ChrX, 13.45 cM
Alliance:	Kdm6atm1c(EUCOMM)Jae page

Germline Transmission:	Earliest citation of germline transmission: J:188485
Parent Cell Line:	v6.5 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S4/SvJae)F1

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A targeting vector, obtained from EUCOMM, containing a FRT site flanked beta-geo cassette and a loxP site was inserted upstream of exon 3. A second loxP site was inserted downstream of exon 3. ES cells were transiently transfected with a FLP recombinase vector to remove the selection cassette. (J:188485)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kdm6a Mutation:	38 strains or lines available

Original:	J:188485 Welstead GG, et al., X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner. Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):13004-9
All:	9 reference(s)