Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(tetO-AIMP2)630Tmd
Name:	transgene insertion 630, Ted M Dawson
MGI ID:	MGI:5506893
Transgene:	Tg(tetO-AIMP2)630Tmd  Location: unknown
Alliance:	Tg(tetO-AIMP2)630Tmd page

Strain of Origin:

B6C3F2

Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence) Inducer:    doxycycline/tetracycline Mutation:    Insertion   Tg(tetO-AIMP2)630Tmd expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human AIMP2 (7965) Aimp2  (MGI:2385237)   Tg(tetO-AIMP2)630Tmd expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified tetO   Mutation details: The C-terminal FLAG-tagged human aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 (AIMP2) gene was placed under control of a tetO promoter. (J:200063)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:200063 Lee Y, et al., Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss. Nat Neurosci. 2013 Oct;16(10):1392-400
All:	1 reference(s)