Gene Expression Data
Assay Details
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Assay
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Reference:
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J:95017
Parlato R, et al., An integrated regulatory network controlling survival and migration in thyroid organogenesis. Dev Biol. 2004 Dec 15;276(2):464-75
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5495929
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Gene symbol:
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Foxe1
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Gene name:
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forkhead box E1
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Antibody:
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anti-TTF2
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Results
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Specimen
1I:
embryonic day 9.0
(more  )
Specimen
1I:
(close  )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
1J:
(close )
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Genetic Background:
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B6.129P2-Hhextm1Rbe
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Mutant Allele(s):
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Hhextm1Rbe/Hhextm1Rbe
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
1K:
embryonic day 10.0
(more )
Specimen
1K:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
1L:
(close )
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Genetic Background:
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B6.129P2-Hhextm1Rbe
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Mutant Allele(s):
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Hhextm1Rbe/Hhextm1Rbe
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: thyroid primordium |
Trace |
Single cells |
1L
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Strong reduction in expression level, compared with those of the wild type. Only a few non-migrating cells can still be detected.
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| TS16: pharynx epithelium |
Present |
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1L
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Expression in the endodermal cells of the pharynx is preserved.
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Specimen
2E:
embryonic day 9.0
(more )
Specimen
2E:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
2F:
(close )
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Genetic Background:
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B6.129S4-Nkx2-1tm1Shk
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Mutant Allele(s):
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Nkx2-1tm1Shk/Nkx2-1tm1Shk
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
2G:
embryonic day 10.0
(more )
Specimen
2G:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
2H:
(close )
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Genetic Background:
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B6.129S4-Nkx2-1tm1Shk
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Mutant Allele(s):
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Nkx2-1tm1Shk/Nkx2-1tm1Shk
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
3E:
embryonic day 9.0
(more )
Specimen
3E:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
3F:
(close )
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Genetic Background:
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B6.129-Pax8tm1Pgr
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Mutant Allele(s):
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Pax8tm1Pgr/Pax8tm1Pgr
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: thyroid primordium |
Ambiguous |
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3F
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Dramatic decrease in expression level, compared with those of the wild type.
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| TS14: foregut epithelium |
Present |
Regionally restricted |
3F
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Expressed in the cells neighboring the thyroid anlage. Expression is comparable to those of the wild-type.
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Specimen
3G:
embryonic day 10.0
(more )
Specimen
3G:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
3H:
(close )
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Genetic Background:
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B6.129-Pax8tm1Pgr
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Mutant Allele(s):
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Pax8tm1Pgr/Pax8tm1Pgr
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
5C:
embryonic day 11.0
(more )
Specimen
5C:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
5D:
(close )
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Genetic Background:
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B6.129-Pax8tm1Pgr
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Mutant Allele(s):
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Pax8tm1Pgr/Pax8tm1Pgr
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
7G:
embryonic day 10.0
(more )
Specimen
7G:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
7J:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Shhtm1Chg/Shhtm1Chg
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
not shown:
(close )
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Genetic Background:
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B6.129-Foxe1tm1Rdl Nkx2-1tm1Rdl
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Mutant Allele(s):
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Foxe1tm1Rdl/Foxe1tm1Rdl
Nkx2-1tm1Rdl/Nkx2-1+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
not shown:
(close )
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Genetic Background:
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B6.129-Nkx2-1tm1Rdl
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Mutant Allele(s):
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Nkx2-1tm1Rdl/Nkx2-1+
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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