Foxe1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:95017 Parlato R, et al., An integrated regulatory network controlling survival and migration in thyroid organogenesis. Dev Biol. 2004 Dec 15;276(2):464-75
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5495929
Gene symbol:	Foxe1
Gene name:	forkhead box E1

Antibody:	anti-TTF2
Detection system:	Secondary antibody coupled to horseradish peroxidase

Results

1I ©

Specimen 1I: embryonic day 9.0 (more

)

Structure	Level	Pattern	Image	Note
TS14: thyroid primordium	Present		1I

1J ©

Specimen 1J: embryonic day 9.0; Hhex^tm1Rbe/Hhex^tm1Rbe (more

)

Structure	Level	Pattern	Image	Note
TS14: thyroid primordium	Present		1J	Expression is comparable to the wild type.

1K ©

Specimen 1K: embryonic day 10.0 (more

)

Structure	Level	Pattern	Image	Note
TS16: thyroid primordium	Present		1K
TS16: pharynx epithelium	Present		1K

1L ©

Specimen 1L: embryonic day 10.0; Hhex^tm1Rbe/Hhex^tm1Rbe (more

)

Structure	Level	Pattern	Image	Note
TS16: thyroid primordium	Trace	Single cells	1L	Strong reduction in expression level, compared with those of the wild type. Only a few non-migrating cells can still be detected.
TS16: pharynx epithelium	Present		1L	Expression in the endodermal cells of the pharynx is preserved.

2E ©

Specimen 2E: embryonic day 9.0 (more

)

Structure	Level	Pattern	Image	Note
TS14: thyroid primordium	Present		2E

2F ©

Specimen 2F: embryonic day 9.0; Nkx2-1^tm1Shk/Nkx2-1^tm1Shk (more

)

Structure	Level	Pattern	Image	Note
TS14: thyroid primordium	Present		2F	Expression is comparable to those of the wild-type bud.

2G ©

Specimen 2G: embryonic day 10.0 (more

)

Structure	Level	Pattern	Image	Note
TS16: pharynx epithelium	Present		2G
TS16: thyroid primordium	Present		2G

2H ©

Specimen 2H: embryonic day 10.0; Nkx2-1^tm1Shk/Nkx2-1^tm1Shk (more

)

Structure	Level	Pattern	Image	Note
TS16: thyroid primordium	Ambiguous		2H	Strong reduction in expression level, compared with those of the wild type.
TS16: pharynx epithelium	Present		2H	Expression in the endodermal cells of the pharynx is preserved.

3E ©

Specimen 3E: embryonic day 9.0 (more

)

Structure	Level	Pattern	Image	Note
TS14: thyroid primordium	Present		3E
TS14: foregut epithelium	Present	Regionally restricted	3E	Expressed in the cells neighboring the thyroid anlage.

3F ©

Specimen 3F: embryonic day 9.0; Pax8^tm1Pgr/Pax8^tm1Pgr (more

)

Structure	Level	Pattern	Image	Note
TS14: thyroid primordium	Ambiguous		3F	Dramatic decrease in expression level, compared with those of the wild type.
TS14: foregut epithelium	Present	Regionally restricted	3F	Expressed in the cells neighboring the thyroid anlage. Expression is comparable to those of the wild-type.

3G ©

Specimen 3G: embryonic day 10.0 (more

)

Structure	Level	Pattern	Image	Note
TS16: thyroid primordium	Present		3G
TS16: pharynx epithelium	Present		3G

3H ©

Specimen 3H: embryonic day 10.0; Pax8^tm1Pgr/Pax8^tm1Pgr (more

)

Structure	Level	Pattern	Image	Note
TS16: thyroid primordium	Absent		3H
TS16: pharynx epithelium	Present		3H

5C ©

Specimen 5C: embryonic day 11.0 (more

)

Structure	Level	Pattern	Image	Note
TS18: pharynx epithelium	Present		5C
TS18: thyroid gland	Present		5C

5D ©

Specimen 5D: embryonic day 11.0; Pax8^tm1Pgr/Pax8^tm1Pgr (more

)

Structure	Level	Pattern	Image	Note
TS18: thyroid gland	Absent		5D
TS18: pharynx epithelium	Present		5D

7G ©

Specimen 7G: embryonic day 10.0 (more

)

Structure	Level	Pattern	Image	Note
TS16: pharynx epithelium	Present		7G
TS16: thyroid primordium	Present		7G

7J ©

Specimen 7J: embryonic day 10.0; Shh^tm1Chg/Shh^tm1Chg (more

)

Structure	Level	Pattern	Image	Note
TS16: thyroid primordium	Present		7J	Expression is comparable to the wild type.
TS16: pharynx epithelium	Absent		7J	Loss of expression.

Specimen not shown: embryonic day 10.5; Foxe1^tm1Rdl/Foxe1^tm1Rdl, Nkx2-1^tm1Rdl/Nkx2-1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: thyroid primordium	Weak
TS17: pharynx epithelium	Absent

Specimen not shown: postnatal; Nkx2-1^tm1Rdl/Nkx2-1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: diencephalon	Present
TS28: lung	Present

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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