Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:77801
Soo K, et al., Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo. Dev Biol. 2002 Jul 15;247(2):251-70
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:5491319
|
|
Gene symbol:
|
Dmbx1
|
|
Gene name:
|
diencephalon/mesencephalon homeobox 1
|
|
Probe:
|
Dmbx1 probe1
|
|
Probe preparation:
|
Antisense labelled with digoxigenin RNA
|
|
|
Results
|
Specimen
2C +/+:
embryonic day 10.5
(more  )
Specimen
2C +/+:
(close  )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: diencephalon |
Present |
Regionally restricted |
2C +/+
|
Expression was in the dorsal and lateral neuroepithelium of the diencephalon and the midbrain, including the diencephalon-midbrain junction.
|
| TS17: midbrain |
Present |
Regionally restricted |
2C +/+
|
Expression was in the dorsal and lateral neuroepithelium of the diencephalon and the midbrain, including the diencephalon-midbrain junction.
|
Specimen
2C -/-:
(close )
|
Genetic Background:
|
involves: 129S7/SvEvBrd * C57BL/6
|
|
Mutant Allele(s):
|
Twist1tm1Bhr/Twist1tm1Bhr
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: brain |
Present |
Regionally restricted |
2C -/-
|
Expression was reduced or absent in the tissues anterior to the expression domain that resembles the diencephalon-midbrain junction.
|
Specimen
3E +/+:
embryonic day 10.5
(more )
Specimen
3E +/+:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: diencephalon |
Present |
Regionally restricted |
3E +/+
|
Expression was detected in the dorsal region.
|
| TS17: midbrain |
Present |
Regionally restricted |
3E +/+
|
Expression was detected in the dorsal region.
|
Specimen
3E -/-:
(close )
|
Genetic Background:
|
involves: 129S7/SvEvBrd * C57BL/6
|
|
Mutant Allele(s):
|
Twist1tm1Bhr/Twist1tm1Bhr
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: diencephalon |
Present |
|
3E -/-
|
Expression was detected in the lateral region in the presumptive diencephalon and midbrain regions of the exposed neural plate in the mutant.
|
| TS17: midbrain |
Present |
|
3E -/-
|
Expression was detected in the lateral region in the presumptive diencephalon and midbrain regions of the exposed neural plate in the mutant.
|
|
Analysis Tools