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Gene Expression Data
Assay Details
Assay
Reference: J:136716 Simmons DG, et al., Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth. Development. 2008 Jun;135(12):2083-91
Assay type: RNA in situ
MGI Accession ID: MGI:5488779
Gene symbol: Synb
Gene name: syncytin b
Probe: Synb cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1 E7.5: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: extraembryonic component Absent 1_E7.5 Synb

Specimen 1 E8.5: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: labyrinthine zone Present Regionally restricted 1_E8.5 Synb Expression is in clusters of trophoblast cells at the chorioallantoic interface and in some cases in cells at the initial branch points.

Specimen 1 E9.0: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: labyrinthine zone Present 1_E9.0 Synb Expression is in elongated trophoblast cells adjacent to the fetal endothelial cells.

Specimen 1 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: labyrinthine zone Present Regionally restricted 1_E14.5 Synb Expression is in elongated trophoblast cells adjacent to the fetal endothelial cells.

Specimen 2B: embryonic day 14.5 (more )
Note: Double labeled: purple - Synb; brown - Syna (assay MGI:5488796).
Structure Level Pattern Image Note
TS22: labyrinthine zone Present Regionally restricted 2B , 2B right Expression is in syncytiotrophoblast layer II cells.

Specimen 2C: embryonic day 14.5 (more )
Note: Double labeled: purple - Synb; brown - Ctsq (assay MGI:5488793).
Structure Level Pattern Image Note
TS22: labyrinthine zone Present 2C , 2C right

Specimen 3A: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: extraembryonic component Present Regionally restricted 3A Synb Expression is in clusters of cells at the basal side of the chorion.
TS14: labyrinthine zone Present Regionally restricted 3A Synb Expression is in syncytiotrophoblast layer II cells.

Specimen not shown: embryonic day 8.5; Gcm1tm1Jcc/Gcm1tm1Jcc (more )
Structure Level Pattern Image Note
TS13: extraembryonic component Absent

Specimen 4 Het: embryonic day 9.5; Gcm1tm1Jcc/Gcm1+ (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present 4_Het Synb
TS28: placenta Present 4_Het Synb

Specimen 4 Gcm1 KO: embryonic day 9.5; Gcm1tm1Jcc/Gcm1tm1Jcc (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Absent 4_Gcm1 KO Synb
TS28: placenta Absent 4_Gcm1 KO Synb

Specimen 4 Double Het: embryonic day 9.5; Cebpatm1Gjd/Cebpa+, Cebpbtm1Pfj/Cebpb+ (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present 4_Double Het Synb
TS28: placenta Present 4_Double Het Synb

Specimen 4 Cebpa KO: embryonic day 9.5; Cebpatm1Gjd/Cebpatm1Gjd (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present 4_Cebpa KO Synb Expression in this mutant is the same as in wild type.
TS28: placenta Present 4_Cebpa KO Synb Expression in this mutant is the same as in wild type.

Specimen 4 Cebpb KO: embryonic day 9.5; Cebpbtm1Pfj/Cebpbtm1Pfj (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present 4_Cebpb KO Synb Expression in this mutant is the same as in wild type.
TS28: placenta Present 4_Cebpb KO Synb Expression in this mutant is the same as in wild type.

Specimen 4 Double KO: embryonic day 9.5; Cebpatm1Gjd/Cebpatm1Gjd, Cebpbtm1Pfj/Cebpbtm1Pfj (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present 4_Double KO Synb Expression in this mutant is the same as in wild type.
TS28: placenta Present 4_Double KO Synb Expression in this mutant is the same as in wild type.

Specimen 5 WT E8.5: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: extraembryonic component Present 5_Synb E8.5 WT

Specimen 5 -/- E8.5: embryonic day 8.5; Gcm1tm1Jcc/Gcm1tm1Jcc (more )
Structure Level Pattern Image Note
TS13: extraembryonic component Absent 5_Synb E8.5 -/-

Specimen 5 WT E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present 5_Synb E9.5 WT

Specimen 5 -/- E9.5: embryonic day 9.5; Gcm1tm1Jcc/Gcm1tm1Jcc (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Absent 5_Synb E9.5 -/-


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory