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Gene Expression Data
Assay Details
Assay
Reference: J:136716 Simmons DG, et al., Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth. Development. 2008 Jun;135(12):2083-91
Assay type: RNA in situ
MGI Accession ID: MGI:5488640
Gene symbol: Gcm1
Gene name: glial cells missing homolog 1
Probe: Gcm1 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1 E7.5: embryonic day 7.5 (more )
Note: Magnification is of the boxed area.
Structure Level Pattern Image Note
TS11: trophectoderm Present 1_E7.5 Gcm1 , 1_top E7.5

Specimen 1 E8.5: embryonic day 8.5 (more )
Note: Magnification is of the boxed area.
Structure Level Pattern Image Note
TS13: labyrinthine zone Present Regionally restricted 1_top E8.5 , 1_E8.5 Gcm1 Expression is in clusters of trophoblast cells at the chorioallantoic interface and in some cases in cells at the initial branch points.

Specimen 1 E9.0: embryonic day 9.0 (more )
Note: Magnification is of the boxed area.
Structure Level Pattern Image Note
TS14: labyrinthine zone Present Regionally restricted 1_E9.0 Gcm1 , 1_top E9.0 Expression is in elongated trophoblast cells adjacent to the fetal endothelial cells.

Specimen 1 E14.5: embryonic day 14.5 (more )
Note: Magnification is of the boxed area.
Structure Level Pattern Image Note
TS22: labyrinthine zone Present Regionally restricted 1_E14.5 Gcm1 , 1_top E14.5 Expression is in elongated trophoblast cells adjacent to the fetal endothelial cells.

Specimen 3A: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: extraembryonic component Present Regionally restricted 3A Gcm1 Expression is in clusters of cells at the basal side of the chorion.
TS14: labyrinthine zone Present Regionally restricted 3A Gcm1 Expression is in syncytiotrophoblast layer II cells.

Specimen 4 Het: embryonic day 9.5; Gcm1tm1Jcc/Gcm1+ (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present 4_Het Gcm1
TS28: placenta Present 4_Het Gcm1

Specimen 4 Gcm1 KO: embryonic day 9.5; Gcm1tm1Jcc/Gcm1tm1Jcc (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Absent 4_Gcm1 KO Gcm1
TS28: placenta Absent 4_Gcm1 KO Gcm1

Specimen 4 Double Het: embryonic day 9.5; Cebpatm1Gjd/Cebpa+, Cebpbtm1Pfj/Cebpb+ (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present 4_Double Het Gcm1
TS28: placenta Present 4_Double Het Gcm1

Specimen 4 Cebpa KO: embryonic day 9.5; Cebpatm1Gjd/Cebpatm1Gjd (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present 4_Cebpa KO Gcm1 Expression in this mutant is the same as in wild type.
TS28: placenta Present 4_Cebpa KO Gcm1 Expression in this mutant is the same as in wild type.

Specimen 4 Cebpb KO: embryonic day 9.5; Cebpbtm1Pfj/Cebpbtm1Pfj (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present 4_Cebpb KO Gcm1 Expression in this mutant is the same as in wild type.
TS28: placenta Present 4_Cebpb KO Gcm1 Expression in this mutant is the same as in wild type.

Specimen 4 Double KO: embryonic day 9.5; Cebpatm1Gjd/Cebpatm1Gjd, Cebpbtm1Pfj/Cebpbtm1Pfj (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present 4_Double KO Gcm1 Expression in this mutant is the same as in wild type.
TS28: placenta Present 4_Double KO Gcm1 Expression in this mutant is the same as in wild type.

Specimen 5 WT E8.5: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: extraembryonic component Present 5_Gcm1 E8.5 WT

Specimen 5 -/- E8.5: embryonic day 8.5; Gcm1tm1Jcc/Gcm1tm1Jcc (more )
Structure Level Pattern Image Note
TS13: extraembryonic component Absent 5_Gcm1 E8.5 -/-

Specimen 5 WT E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present 5_Gcm1 E9.5 WT

Specimen 5 -/- E9.5: embryonic day 9.5; Gcm1tm1Jcc/Gcm1tm1Jcc (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Absent 5_Gcm1 E9.5 -/-


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory