Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prkcztm1.1Rlh
Name:	protein kinase C, zeta; targeted mutation 1.1, Richard L Huganir
MGI ID:	MGI:5485243
Synonyms:	PKCzetafl, PKCzeta//PKM-zetafl
Gene:	Prkcz  Location: Chr4:155344586-155445818 bp, - strand  Genetic Position: Chr4, 86.17 cM, cytoband E2
Alliance:	Prkcztm1.1Rlh page

Germline Transmission:	Earliest citation of germline transmission: J:194557
Parent Cell Line:	MC1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exon 11 was floxed. Flp-mediated recombination removed an FRT-flanked neo cassette inserted downstream of exon 10 (initially described as exon 11) of the canonical sequence. (J:194557)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Prkcz Mutation:	43 strains or lines available

Original:	J:194557 Volk LJ, et al., PKM-zeta is not required for hippocampal synaptic plasticity, learning and memory. Nature. 2013 Jan 17;493(7432):420-3
All:	1 reference(s)