Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cxcr3tm1Arsa
Name:	C-X-C motif chemokine receptor 3; targeted mutation 1, Abhay R Satoskar
MGI ID:	MGI:5478545
Synonyms:	CIBER, Cxcr3GFP
Gene:	Cxcr3  Location: ChrX:100775141-100777753 bp, - strand  Genetic Position: ChrX, 44.58 cM
Alliance:	Cxcr3tm1Arsa page

Germline Transmission:	Earliest citation of germline transmission: J:193492
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: An IRES, EGFP and floxed pgk-neo cassette were inserted in the 3' untranslated region of exon 2. Protein expression in activated T cells from mutant mice is similar to wild-type controls. Expression pattern of EGFP matches endogenous protein expression. (J:193492)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cxcr3 Mutation:	10 strains or lines available

Original:	J:193492 Oghumu S, et al., Distinct Populations of Innate CD8+ T Cells Revealed in a CXCR3 Reporter Mouse. J Immunol. 2013 Mar 1;190(5):2229-40
All:	9 reference(s)