Adartm1b(EUCOMM)Wtsi
Targeted Allele Detail
|
Symbol: |
Adartm1b(EUCOMM)Wtsi |
Name: |
adenosine deaminase, RNA-specific; targeted mutation 1b, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:5474756 |
Gene: |
Adar Location: Chr3:89622329-89660753 bp, + strand Genetic Position: Chr3, 39.19 cM, cytoband F2
|
Alliance: |
Adartm1b(EUCOMM)Wtsi page
|
IMPC: |
Adar gene page |
|
Mutant Cell Line: |
EPD0087_1_D11 |
Germline Transmission: |
Earliest citation of germline transmission:
J:188991
|
Parent Cell Line: |
JM8.F6 (ES Cell)
|
Strain of Origin: |
C57BL/6N
|
Project Collection: |
EUCOMM
|
|
Allele Type: |
|
Targeted (Null/knockout, Reporter) |
Mutations: |
|
Insertion, Intragenic deletion
Vector: L1L2_gt0
|
|
|
Mutation details: The L1L2_gt0 cassette was inserted at position 89646067 of Chromosome 3 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 89646817. The critical exon(s) were thus flanked by loxP sites and subsequent cre expression then excised this critical sequence resulting in a reporter knockout allele. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
(J:155845, J:173534, J:188991)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
|
Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
6 reference(s) |
|