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Gene Expression Data
Assay Details
Assay
Reference: J:35033 Srivastava D, et al., A subclass of bHLH proteins required for cardiac morphogenesis. Science. 1995 Dec 22;270(5244):1995-9
Assay type: RNA in situ
MGI Accession ID: MGI:5469632
Gene symbol: Hand2
Gene name: heart and neural crest derivatives expressed 2
Probe: dHAND cDNA3
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2A/B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: bulbus cordis Present 2A/B
TS13: outflow tract Present Regionally restricted 2A/B Expressed in aortic sac.
TS13: primitive ventricle Present 2A/B Expressed in the future left ventricle.
Specimen 2C/D: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: somatopleure Present 2C/D
TS13: splanchnopleure Present 2C/D
Specimen 2E/F: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 1st arch artery Strong 2E/F Expressed in the first aortic arch.
TS15: 2nd arch artery Strong 2E/F Expressed in the second aortic arch.
TS15: outflow tract Strong 2E/F
TS15: cardinal vein Present 2E/F
TS15: heart atrium Present 2E/F
TS15: primitive ventricle Present 2E/F
TS15: sinus venosus Present 2E/F
Specimen not shown: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Absent
TS11: extraembryonic component Absent
TS28: decidua Present
Specimen not shown: embryonic day 7.75 (more )
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present
Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch Strong
TS17: 3rd arch artery Strong
TS17: 4th arch artery Strong
TS17: outflow tract Strong Regionally restricted Expressed in truncus arteriosus.
TS17: branchial arch artery Strong Regionally restricted Expressed in the aortic sac.
TS17: cardinal vein Present
TS17: heart atrium Present
TS17: primitive ventricle Present
TS17: sinus venosus Present
Specimen not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS22: heart Absent
TS22: adrenal medulla Present
TS22: peripheral nerve trunk Present
Specimen not shown: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: embryo Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory