Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Or8a1btm1.1(COP4*/EYFP)Tboz
Name:	olfactory receptor family 8 subfamily A member 1B; targeted mutation 1.1, Thomas Bozza
MGI ID:	MGI:5469474
Synonyms:	M72-ChR2, M72-ChR2-YFP, M72-IRES-ChR2-YFP
Gene:	Or8a1b  Location: Chr9:37622644-37623576 bp, - strand  Genetic Position: Chr9, 20.8 cM
Alliance:	Or8a1btm1.1(COP4*/EYFP)Tboz page

Germline Transmission:	Earliest citation of germline transmission: J:240731
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert an internal ribosome entry site (IRES), the ChR2(H134R)-EYFP fusion gene, and a self-excising neo cassette, ACNF, downstream of the olfactory receptor 160 gene. The neo cassette is excised. Only olfactory sensory neurons (OSN) expressing this specific odorant receptor, M72, express ChR2(H134R)-EYFP, rendering them light sensitive. (J:240731)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Or8a1b Mutation:	35 strains or lines available

Original:	J:240731 Smear M, et al., Multiple perceptible signals from a single olfactory glomerulus. Nat Neurosci. 2013 Nov;16(11):1687-91
All:	9 reference(s)