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Gene Expression Data
Assay Details
Assay
Reference: J:22651 Manova K, et al., mRNAs for activin receptors II and IIB are expressed in mouse oocytes and in the epiblast of pregastrula and gastrula stage mouse embryos. Mech Dev. 1995 Jan;49(1-2):3-11
Assay type: RNA in situ
MGI Accession ID: MGI:5469098
Gene symbol: Acvr2b
Gene name: activin receptor IIB
Probe: Acvr2b cDNA2
Probe preparation: labelled with P33 DNA
Visualized with: Autoradiography
Assay notes: An alternate probe (MGI:5469086) may have been used; authors report that probe gave similar results.
Results
Specimen 2B: postnatal (more )
Structure Level Pattern Image Note
TS28: ovary Present Regionally restricted 2B Lower expression in theca and interstitial cells than in follicle cells.
TS28: ovary follicle Present 2B
TS28: ovary theca Weak 2B
TS28: oocyte Present 2B

Specimen 3C: postnatal day 13 (more )
Structure Cell Type Level Pattern Image Note
TS28: spermatogonium Present 3C
TS28: Sertoli cell Sertoli cell Present 3C

Specimen not shown E4.5: embryonic day 4.5 (more )
Structure Level Pattern Image Note
TS5: inner cell mass Strong Significant expression in the inner cell mass and trophectoderm of one of two embryos examined.
TS5: trophectoderm Strong Significant expression in the inner cell mass and trophectoderm of one of two embryos examined.

Specimen 4A/D: embryonic day 5.5 (more )
Structure Level Pattern Image Note
TS7: ectoplacental cone Present 4A/D
TS7: epiblast Present 4A/D
TS7: extraembryonic ectoderm Present 4A/D
TS7: mural trophectoderm Present 4A/D

Specimen 4B/E: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: ectoplacental cone Strong 4B/E
TS9: embryo ectoderm Strong 4B/E
TS9: extraembryonic ectoderm Moderate 4B/E
TS9: extraembryonic visceral endoderm Absent 4B/E No expression in visceral endoderm around upper two-thirds of egg cylinder.
TS9: primary trophoblast giant cell Absent 4B/E

Specimen 4C/F embryo: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo ectoderm Strong 4C/F
TS11: embryo mesoderm Strong 4C/F
TS11: future spinal cord neural plate Present 4C/F
TS11: extraembryonic ectoderm Moderate 4C/F
TS11: allantois Strong 4C/F
TS11: amnion Moderate 4C/F
TS11: chorion Moderate 4C/F
TS11: ectoplacental cone Moderate 4C/F
TS11: extraembryonic visceral endoderm Absent 4C/F No expression in external layer of visceral endoderm.

Specimen 4C/F decidua: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS28: decidua Weak 4C/F Moderate to low expression in the decidua.

Specimen 5A/B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Present Widespread 5A/B Expression in all embryonic tissues.
TS13: embryo mesenchyme Strong 5A/B
TS13: neural ectoderm Strong 5A/B

Specimen 5C/D: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: trophoblast giant cell Present Regionally restricted 5C/D Expression in giant trophoblast cells lining inner surface of decidua.

Specimen 5E/F: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: chorion Present 5E/F

Specimen not shown E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: brain Present

Specimen 6A/B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: renal tubule Present 6A/B
TS21: spinal cord Present 6A/B

Specimen 6C/D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: intestine epithelium Present 6C/D


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory