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Gene Expression Data
Assay Details
Assay
Reference: J:30682 Kawakami A, et al., Developmentally regulated expression of a cell surface protein, neuropilin, in the mouse nervous system. J Neurobiol. 1996 Jan;29(1):1-17
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5468710
Gene symbol: Nrp1
Gene name: neuropilin 1
Antibody: anti-neuropilin
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 4A
TS19: spinal nerve Present 4A
TS19: spinal component of peripheral nervous system Present Regionally restricted 4A Expressed in the dorsal root and the dorsal funiculus.
TS19: neural tube basal columns Present Regionally restricted 4A Expressed in the axons of motor neurons, but not the somata.
TS19: sympathetic ganglion Strong 4A
TS19: trunk mesenchyme Weak Regionally restricted 4A Expressed faintly in the mesenchymal cells surrounding sympathetic ganglia.
TS19: blood vessel Present Regionally restricted 4A Expressed in endothelium.

Specimen 4C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present 4C
TS21: spinal cord lateral wall Present Regionally restricted 4C Expressed in the dorsal spinal cord (afferent fibers of dorsal root ganglion).
TS21: spinal cord floor plate Weak 4C

Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trigeminal nerve Present 5A
TS20: telencephalon Present Regionally restricted 5A Expressed in the olfactory nerve arriving at the olfactory bulb, and in the mitral cells.
TS20: nose Present Regionally restricted 5A Expressed around the nasal cavity (trigeminal nerve, the veins and the olfactory nerve).
TS20: cranial nerve Present Regionally restricted 5A Expressed in the olfactory nerve fibers.
TS20: olfactory epithelium Absent 5A

Specimen 5C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: main olfactory bulb Present Regionally restricted 5C Expressed in the mitral cell layer and the glomeruli.
TS24: olfactory cortex Present Regionally restricted 5C Expressed in the olfactory amygdala. No expression in the olfactory tubercle, piriform cortex, and entorhinal cortex.
TS24: amygdala Present 5C Expressed in the olfactory amygdala.
TS24: piriform cortex Absent 5C
TS24: olfactory lobe Present Regionally restricted 5C Expressed in the olfactory bulb. No expression in the accessory olfactory bulb.
TS24: olfactory nerve Present Regionally restricted 5C Expressed in the lateral olfactory tract.

Specimen 5E: postnatal week 4 (more )
Structure Level Pattern Image Note
TS28: olfactory nerve Strong 5E
TS28: main olfactory bulb glomerular layer Weak 5E Extremely weak in the glomeruli.

Specimen 6A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted 6A Expressed in the hippocampal formation.
TS21: neocortex Present Regionally restricted 6A Expression was confined to the central part of the intermediate zone, but not in the cortical plate or the ventricular zone.

Specimen 6C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hippocampus Present Regionally restricted 6C Expressed in the fimbria, the hippocampal commissura, and the mossy fibers of the granular cells.
TS23: neocortex Present Regionally restricted 6C Expression was confined to the central part of the intermediate zone, but not in the cortical plate or the ventricular zone.

Specimen 6E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: hippocampus Present Regionally restricted 6E Expressed in the fimbria, the hippocampal commissura, and the mossy fibers of the granular cells. No expression in the pyramidal or granular cell layers. Expressed in some cells in the stratum oriens.
TS26: neocortex Weak Regionally restricted 6E Expression was confined to the central part of the intermediate zone, but not in the cortical plate or the ventricular zone.

Specimen 6G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: blood vessel Present Regionally restricted 6G Expressed in capillaries in the ventricular zone of the neocortex and in the pia mater.
TS22: neocortex Present Regionally restricted 6G Expression was confined to the central part of the intermediate zone, but not in the cortical plate or the ventricular zone.

Specimen 6I: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: diencephalon Present Regionally restricted 6I Expressed in the mammillary body.
TS23: telencephalon Present Regionally restricted 6I Expressed in the fornix.

Specimen 7A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: optic nerve Present 7A
TS21: neural retinal epithelium Present Regionally restricted 7A xpressed only in the axons.

Specimen 7C: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: facial ganglion Present 7C
TS18: glossopharyngeal ganglion Present 7C
TS18: trigeminal ganglion Present 7C
TS18: vagus ganglion Present 7C
TS18: acoustic ganglion Absent 7C

Specimen 7E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: pons Present Regionally restricted 7E Expressed in the trigeminal sensory and motor nuclei.

Specimen 7G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebellum Present Regionally restricted 7G Expressed in the axons that form the middle cerebellar peduncle, but not on their cell somata. No expression in the cerebellar cells.
TS24: pons Present Regionally restricted 7G Expressed in the pontine nucleus.

Specimen not shown: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS15: dorsal root ganglion Present

Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neocortex Present Regionally restricted Expression was confined to the central part of the intermediate zone, but not in the cortical plate or the ventricular zone.

Specimen not shown: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: diencephalon Present Regionally restricted Expression in the mammillary body reached a maximal level.

Specimen not shown: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: trigeminal ganglion Present

Specimen not shown: postnatal week 1 (more )
Structure Level Pattern Image Note
TS28: hippocampus Present Expression declined.
TS28: mammillary body Present
TS28: pontine nucleus Absent

Specimen not shown: postnatal week 3 (more )
Structure Level Pattern Image Note
TS28: hippocampus Ambiguous Expression almost disappeared.

Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Weak

Specimen not shown: postnatal (more )
Structure Level Pattern Image Note
TS28: neocortex Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory