Ptf1atm3.1(rtTA)Mgn
Targeted Allele Detail
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Symbol: |
Ptf1atm3.1(rtTA)Mgn |
Name: |
pancreas specific transcription factor, 1a; targeted mutation 3.1, Mark A Magnuson |
MGI ID: |
MGI:5467924 |
Gene: |
Ptf1a Location: Chr2:19450474-19452312 bp, + strand Genetic Position: Chr2, 13.37 cM, cytoband A2
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Alliance: |
Ptf1atm3.1(rtTA)Mgn page
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Germline Transmission: |
Earliest citation of germline transmission:
J:94077
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Parent Cell Line: |
TL1/TL-1 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (RMCE-ready, Transactivator) |
Mutation: |
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Insertion
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Mutation details: A loxP-flanked targeting vector containing a reverse tetracycline transactivator (rtTA) in the 5' UTR and a frt-flanked hygromycin cassette downstream of exon 2 was inserted into the loxed cassette acceptor (LCA) allele by recombinant mediated cassette exchange (RMCE). rtTA is expressed under control of the endogenous Ptf1a promoter. The hygromycin cassette was removed by a flp mediated recombination.
(J:94077)
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Original: |
J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015; |
All: |
4 reference(s) |
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