Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mirc16tm1.2Czc
Name:	microRNA cluster 16, including Mir181d through Mir181c; targeted mutation 1.2, Chang-Zheng Chen
MGI ID:	MGI:5467795
Gene:	Mirc16  Location: Chr8:84905345-84905590 bp  Genetic Position: Chr8, Syntenic

Germline Transmission:	Earliest citation of germline transmission: J:188125
Parent Cell Line:	CGR8 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Cre-mediated recombination removed the cluster. This allele lacks the neo selection cassette. (J:188125)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mirc16 Mutation:	1 strain or line available

Original:	J:188125 Fragoso R, et al., Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1. PLoS Genet. 2012 Aug;8(8):e1002855
All:	1 reference(s)