Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Mirc15tm1.1Czc
Name:	microRNA cluster 15, including Mir181a-2 through Mir181b-2; targeted mutation 1.1, Chang-Zheng Chen
MGI ID:	MGI:5467792
Synonyms:	mir181a2b2f
Gene:	Mirc15  Location: Chr2:38742747-38743930 bp  Genetic Position: Chr2, Syntenic

Germline Transmission:	Earliest citation of germline transmission: J:188125
Parent Cell Line:	CGR8 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: LoxP sites were inserted at least 125 bp upstream and downstream of the cluster. Flp-mediated recombination removed an FRT-flanked neo cassette. (J:188125)

Generation of the Mirc15tm1.1Czc allele

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mirc15 Mutation:	2 strains or lines available

Original:	J:188125 Fragoso R, et al., Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1. PLoS Genet. 2012 Aug;8(8):e1002855
All:	1 reference(s)