Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1Ytchn
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, You-Tzung Chen
MGI ID:	MGI:5465538
Synonyms:	Gt(ROSA)26Sortm1Isyu, Gt(ROSA)26Sortm1Ytch, R26R-GR
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1Ytchn page

Germline Transmission:	Earliest citation of germline transmission: J:191943
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, Reporter) Mutation:    Insertion   Mutation details: An inducible dual fluorescent protein reporter cassette (loxP-Stop-loxP-HIST1H2BB-EGFP-2A-mCherry-GPI-pA; R-GR, which stands for reporter for green-red) was inserted into the locus. HIST1H2BB provides chromatin localization. Removal of the floxed neo/stop cassette is required to obtain expression of EGFP and mCherry in the nucleus and membrane, respectively. (J:191943)

Generation of the Gt(ROSA)26Sortm1Ytchn allele

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:191943 Chen YT, et al., R26R-GR: a Cre-activable dual fluorescent protein reporter mouse. PLoS One. 2012;7(9):e46171
All:	3 reference(s)