Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nfe2l2tm1.1Sred
Name:	nuclear factor, erythroid derived 2, like 2; targeted mutation 1.1, Sekhar P Reddy
MGI ID:	MGI:5463890
Synonyms:	Nrf2f, Nrf2flox
Gene:	Nfe2l2  Location: Chr2:75505857-75534985 bp, - strand  Genetic Position: Chr2, 44.75 cM
Alliance:	Nfe2l2tm1.1Sred page

Germline Transmission:	Earliest citation of germline transmission: J:191916
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6J

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     Exon 5 was floxed. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:191916)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Nfe2l2 Mutation:	88 strains or lines available

Original:	J:191916 Reddy NM, et al., Conditional deletion of Nrf2 in airway epithelium exacerbates acute lung injury and impairs the resolution of inflammation. Am J Respir Cell Mol Biol. 2011 Dec;45(6):1161-8
All:	22 reference(s)