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Mir146tm1Mtm
Targeted Allele Detail
Summary
Symbol: Mir146tm1Mtm
Name: microRNA 146; targeted mutation 1, Michael McManus
MGI ID: MGI:5463573
Gene: Mir146  Location: Chr11:43265224-43265288 bp, - strand  Genetic Position: Chr11, 25.68 cM
Alliance: Mir146tm1Mtm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181752
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsvA targeting vector was designed to insert an FRT site followed by a lacZ gene, a loxP site, a neomycin cassette, an FRT site and a loxP site (FRT-lacZ-loxP-Neo-FRT-loxP) upstream of the microRNA stem loop and one loxP site immediately downstream of the microRNA stem loop. (J:181752)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mir146 Mutation:  9 strains or lines available
References
Original:  J:181831 W.M. Keck Center for Noncoding RNAs, Information obtained from the W.M. Keck Center for Noncoding RNAs. Unpublished. 2012;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory