Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	B3gnt6tm1Lx
Name:	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6; targeted mutation 1, Lijun Xia
MGI ID:	MGI:5447022
Synonyms:	C3GnT-
Gene:	B3gnt6  Location: Chr7:97841622-97848682 bp, - strand  Genetic Position: Chr7, 53.63 cM
Alliance:	B3gnt6tm1Lx page

Germline Transmission:	Earliest citation of germline transmission: J:123826
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A lacZ and neo cassette replaced exon 2. Enzymatic assay confirmed the absence of activity in the colon and ileum. (J:123826)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any B3gnt6 Mutation:	13 strains or lines available

Original:	J:123826 An G, et al., Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans. J Exp Med. 2007 Jun 11;204(6):1417-29
All:	9 reference(s)