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Fnip1tm1.2Baba
Targeted Allele Detail
Summary
Symbol: Fnip1tm1.2Baba
Name: folliculin interacting protein 1; targeted mutation 1.2, Masaya Baba
MGI ID: MGI:5445116
Synonyms: Fnip1d
Gene: Fnip1  Location: Chr11:54329025-54409061 bp, + strand  Genetic Position: Chr11, 32.13 cM
Alliance: Fnip1tm1.2Baba page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:189078
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn FRT-flanked neo cassette with a loxP site was inserted upstream of exon 6. An additional loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the neo cassette and left exon 6 floxed. Cre-mediated recombination removed exon 6. (J:189078)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fnip1 Mutation:  59 strains or lines available
References
Original:  J:189078 Baba M, et al., The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dube syndrome is required for murine B-cell development. Blood. 2012 Aug 9;120(6):1254-61
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory