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Gene Expression Data
Assay Details
Assay
Reference: J:40600 Mayr T, et al., Fritz: a secreted frizzled-related protein that inhibits Wnt activity. Mech Dev. 1997 Apr;63(1):109-25
Assay type: RNA in situ
MGI Accession ID: MGI:5444289
Gene symbol: Frzb
Gene name: frizzled-related protein
Probe: mfiz cDNA2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 5B: embryonic day 7.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS11: embryo ectoderm Present 5A/B Expression is present in the three germ layers of the head process.
TS11: embryo endoderm Present 5A/B Expression is present in the three germ layers of the head process.
TS11: embryo mesenchyme Present 5A/B Expression is present in the three germ layers of the head process.

Specimen 5C: embryonic day 7.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS11: primitive streak Present 5C

Specimen 6B: embryonic day 9.5 (more )
Note: frontal section
Structure Level Pattern Image Note
TS15: forelimb bud Present Graded 6A/B Expression is present ventro-distally.
TS15: extraembryonic component Present Regionally restricted 6A/B Expression is present in the Reichert's membrane.
TS15: neural tube Strong Non-Uniform 6E/F , 6A/B High levels of expression are confined to a medial stripe, with expression levels decreasing toward the roof plate.

Specimen 6D: embryonic day 9.5 (more )
Note: frontal section
Structure Level Pattern Image Note
TS15: hindlimb ridge Present Uniform 6C/D
TS15: neural tube Strong Non-Uniform 6C/D High levels of expression are confined to a medial stripe, with expression levels decreasing toward the roof plate.
TS15: future forebrain Absent 6C/D
TS15: somite Present 6C/D
TS15: head mesenchyme Present 6C/D
TS15: embryo mesenchyme Present Non-Uniform 6C/D The highest levels of expression surround the mesonephric ducts.

Specimen 7A: embryonic day 11.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present Non-Uniform 7A Expression is restricted to the ventricular zone. There is patchy expression in the ventral zone of the intermediate zone.
TS19: dorsal root ganglion Present 7C/D , 7A Expression is present in the dorsal root ganglia and the glial cells ensheathing the dorsal roots.
TS19: dorsal aorta Present 7C/D , 7A
TS19: urinary system Present 7A Expression is present in the urogenital ridge.

Specimen 8B: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: inner ear Present Non-Uniform 8A/B Expression is present the presumptive osteoblastic cells of the capsule of cochlea; there is no expression in chondrocytes.

Specimen 8E: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: mandible Present Non-Uniform 8D/E Expression is present in the presumptive osteoblastic cells, such as in the head of the mandible; there is no expression in chondrocytes.
TS25: cranium Present Non-Uniform 8D/E In the bones of the skull that are formed in a cartilage-indepenent process, expression is found in the presumptive osteoblastic cells.
TS25: zygomatic process Present Non-Uniform 8D/E Expression is found in the presumptive osteoblastic cells of the zygoma.
TS25: ethmoid bone cribriform plate Present Non-Uniform 8D/E Expression is found in the presumptive osteoblastic cells of the lamina cribosa.

Specimen 8H: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: humerus Present Non-Uniform 8G/H Expression is detected in the perichondrium and accumulates in the epiphysial growth plate; there is no expression in chondrocytes.

Specimen Not shown: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: molar Present
TS25: glomerular tuft Present
TS25: renal tubule Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory