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Gucy1b2tm3Mom
Targeted Allele Detail
Summary
Symbol: Gucy1b2tm3Mom
Name: guanylate cyclase 1, soluble, beta 2; targeted mutation 3, Peter Mombaerts
MGI ID: MGI:5444155
Synonyms: Gucy1b2-GFP, Gucy1b2-IRES-tauGFP
Gene: Gucy1b2  Location: Chr14:62630125-62693738 bp, - strand  Genetic Position: Chr14, 33.21 cM
Alliance: Gucy1b2tm3Mom page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:218085
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsAn IRES-tauGFP-ACNF casette was inserted after the stop codon resulting in bicistronic expression of the endogenous protein and the tauGFP marker. (J:218085)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gucy1b2 Mutation:  33 strains or lines available
References
Original:  J:218085 Omura M, et al., Trpc2-expressing sensory neurons in the mouse main olfactory epithelium of type B express the soluble guanylate cyclase Gucy1b2. Mol Cell Neurosci. 2015 Mar;65:114-24
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory