Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fhod3tm1Hsum
Name:	formin homology 2 domain containing 3; targeted mutation 1, Hideki Sumimoto
MGI ID:	MGI:5440613
Synonyms:	Fhod3lacZ
Gene:	Fhod3  Location: Chr18:24841680-25266558 bp, + strand  Genetic Position: Chr18, 13.18 cM
Alliance:	Fhod3tm1Hsum page

Germline Transmission:	Earliest citation of germline transmission: J:187358
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1 was replaced with a lacZ/neo cassette. Western blot analysis confirmed the absence of protein expression in E9.5 embryos. (J:187358)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	100 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fhod3 Mutation:	92 strains or lines available

Original:	J:187358 Kan-o M, et al., Mammalian formin Fhod3 plays an essential role in cardiogenesis by organizing myofibrillogenesis. Biol Open. 2012;1(9):889-896
All:	6 reference(s)