Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Phf10tm1.1Grc
Name:	PHD finger protein 10; targeted mutation 1.1, Gerald R Crabtree
MGI ID:	MGI:5439538
Synonyms:	BAF 45a floxed
Gene:	Phf10  Location: Chr17:15165271-15181535 bp, - strand  Genetic Position: Chr17, 8.95 cM, cytoband A2
Alliance:	Phf10tm1.1Grc page

Germline Transmission:	Earliest citation of germline transmission: J:101977
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting scheme was designed to flank exons 3 and 4 of the gene with loxP sites. A loxP-flanked TK-neomycin cassette was first introduced to intron 4, then excised to leave a single loxP site. The same loxP-flanked TK-neomycin cassette was then placed in intron 2 to create a floxed drug selection marker. Cre-mediated recombination removed the neo cassette and left exons 3 and 4 floxed. (J:101977)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Phf10 Mutation:	27 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	3 reference(s)