Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Antxr2tm1.1Jkit Name: anthrax toxin receptor 2; targeted mutation 1.1, Jan K Kitajewski MGI ID: MGI:5437300 Synonyms: Antxr2- Gene: Antxr2  Location: Chr5:98032547-98178876 bp, - strand  Genetic Position: Chr5, 47.77 cM, cytoband E3 Alliance: Antxr2tm1.1Jkit page

Reproductive tract abnormalities in aged nulliparous Antxr2tm1.1Jkit/Antxr2tm1.1Jkit mice Show the 6 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:187210
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 1 and a floxed neo cassette was inserted downstream of exon 1 via homologous recombination. Cre mediated recombination removed exon 1 and the neo cassette. (J:187210)

Generation of the Antxr2tm1Jkit and Antxr2tm1.1Jkit alleles

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Antxr2 Mutation:	43 strains or lines available

Original:	J:187210 Reeves CV, et al., Anthrax toxin receptor 2 functions in ECM homeostasis of the murine reproductive tract and promotes MMP activity. PLoS One. 2012;7(4):e34862
All:	1 reference(s)