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Camkk2tm1Shyy
Targeted Allele Detail
Summary
Symbol: Camkk2tm1Shyy
Name: calcium/calmodulin-dependent protein kinase kinase 2, beta; targeted mutation 1, John Y J Shyy
MGI ID: MGI:5437264
Synonyms: CaMKKbeta-
Gene: Camkk2  Location: Chr5:122869233-122917472 bp, - strand  Genetic Position: Chr5, 62.55 cM
Alliance: Camkk2tm1Shyy page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:187027
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette replaced exons 2 through 5. Western blot analysis confirmed the absence of protein expression in the epididymal fat pad. (J:187027)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Camkk2 Mutation:  40 strains or lines available
References
Original:  J:187027 Peng IC, et al., Glucagon regulates ACC activity in adipocytes through the CAMKKbeta/AMPK pathway. Am J Physiol Endocrinol Metab. 2012 Jun 15;302(12):E1560-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory