Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Fktntm1Kcam
Name:	fukutin; targeted mutation 1, Kevin P Campbell
MGI ID:	MGI:5435571
Gene:	Fktn  Location: Chr4:53713745-53765785 bp, + strand  Genetic Position: Chr4, 28.74 cM
Alliance:	Fktntm1Kcam page

Germline Transmission:	Earliest citation of germline transmission: J:187144
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site and an FRT flanked neo selection cassette were inserted upstream of exon 2 while a second loxP site was inserted downstream. (J:187144)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fktn Mutation:	44 strains or lines available

Original:	J:187144 Beedle AM, et al., Mouse fukutin deletion impairs dystroglycan processing and recapitulates muscular dystrophy. J Clin Invest. 2012 Sep 4;122(9):3330-42
All:	4 reference(s)