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Htttm2Xen
Targeted Allele Detail
Summary
Symbol: Htttm2Xen
Name: huntingtin; targeted mutation 2, Taconic Biosciences
MGI ID: MGI:5426950
Synonyms: Htttm2(HTT*Q48)Xen
Gene: Htt  Location: Chr5:34919084-35069878 bp, + strand  Genetic Position: Chr5, 17.92 cM
Alliance: Htttm2Xen page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:147112
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Humanized sequence)
Mutation:    Insertion
 
Mutation details: A construct carrying human exon 1 of Huntington gene with 80 CAG repeats (~80 glutamine expansions) was targeted to mouse Huntington gene replacing mouse exon 1 of the gene. (J:147112)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Htt Mutation:  179 strains or lines available
References
Original:  J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory