Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(SNCA)129Mjff
Name:	transgene insertion 129, The Michael J Fox Foundation
MGI ID:	MGI:5424882
Synonyms:	MJFF-9 SNCA WT line 129
Transgene:	Tg(SNCA)129Mjff  Location: Chr7:77253912-77254810 bp  Genetic Position: Chr7, Syntenic
Alliance:	Tg(SNCA)129Mjff page

Strain of Origin:

C57BL/6NTac

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutations:    Insertion, Intergenic deletion   Tg(SNCA)129Mjff expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human SNCA (6622) Snca  (MGI:1277151)   Mutation details: The human bacterial artificial chromosome (BAC) RP1-458H10, containing the entire synuclein, alpha (non A4 component of amyloid precursor), SNCA, gene was used as the source for the SNCA-Wt transgene, which was linearized and microinjected into the pronucleus of C57BL/6NTac fertilized eggs. Transgene insertion occurred on Chr 7, causing a 898 bp deletion.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	2 reference(s)