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Gene Expression Data
Assay Details
Assay
Reference: J:71421 Loes S, et al., Slit1 is specifically expressed in the primary and secondary enamel knots during molar tooth cusp formation. Mech Dev. 2001 Sep;107(1-2):155-7
Assay type: RNA in situ
MGI Accession ID: MGI:5424361
Gene symbol: Robo2
Gene name: roundabout guidance receptor 2
Probe: Robo2 cDNA4
Probe preparation: Antisense labelled with S35 RNA
Assay notes: The exact developmental stages of the tooth germs were judged from the tissue sections according to morphological criteria.
Results
Specimen 1E1: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch mesenchyme Present 1E1 Expression is in dental and jaw mesenchyme.
Specimen 1E2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: oral region Present Regionally restricted 1E2 Expression is in dental mesenchyme.
TS19: jaw primordium mesenchyme Present 1E2
Specimen 1E3: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral region Present Regionally restricted 1E3 Expression is in dental mesenchyme.
TS20: jaw primordium mesenchyme Present 1E3
Specimen 1E4: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: molar epithelium Present 1E4
TS21: tooth bud Present 1E4
Specimen 1E5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: molar mesenchyme Weak Regionally restricted 1E5 Expression is in mesenchymal cells next to the cervical loops.
TS22: dental papilla Weak 1E5
TS22: inner enamel epithelium Present 1E5
TS22: molar epithelium Present 1E5
TS22: cap stage tooth Present Regionally restricted 1E5
Specimen 1E6: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: molar mesenchyme Present Regionally restricted 1E6 Expression is in mesenchymal cells next to the cervical loops.
TS24: molar dental papilla Present 1E6
TS24: bell stage tooth Present 1E6
Specimen 1E7: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: molar mesenchyme Present Regionally restricted 1E7 Expression is in mesenchymal cells next to the cervical loops.
TS26: dental papilla Present 1E7
TS26: bell stage tooth Present 1E7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory