Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Capn1tm1Dgen
Name:	calpain 1; targeted mutation 1, Deltagen
MGI ID:	MGI:5319092
Gene:	Capn1  Location: Chr19:6038573-6065855 bp, - strand  Genetic Position: Chr19, 4.34 cM
Alliance:	Capn1tm1Dgen page

Germline Transmission:	Earliest citation of germline transmission: J:183585
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd
Project Collection:	Deltagen

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion     A lacZ-neo cassette was inserted into the gene. (J:183585)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Capn1 Mutation:	33 strains or lines available

Original:	J:183585 Scalia R, et al., A novel role for calpain in the endothelial dysfunction induced by activation of angiotensin II type 1 receptor signaling. Circ Res. 2011 Apr 29;108(9):1102-11
All:	2 reference(s)