Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Del(5Limk1-Trim50)2Uta
Name:	deletion, Chr 5, Uta Francke 2
MGI ID:	MGI:5317121
Synonyms:	DD, Del2Uta
Gene:	Del(5Limk1-Trim50)2Uta  Location: Chr5:134684893-135396859 bp  Genetic Position: Chr5, Syntenic

Germline Transmission:	Earliest citation of germline transmission: J:182796
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutations:    Intergenic deletion, Intragenic deletion   Del(5Limk1-Trim50)2Uta involves 28 genes/genome features (Gm25315, Limk1, Gm10369 ...) View all   Mutation details: Cre-mediated recombination of ES cells carrying Limk1tm1Uta and Trim50tm1Uta removed all genomic sequence between the two alleles (including Limk1, Eln, Wbscr26, Cldn13, Wbscr27, Cldn4, Cldn3, Abhd11, Stx1a, Wbscr22, Wbscr18, Vps37d, Mlxipl, Tbl2, Bcl7b, Baz1b, Fzd9, Fkbp6 and Trim50). (J:182796)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Del(5Limk1-Trim50)2Uta Mutation:	1 strain or line available

Original:	J:182796 Li HH, et al., Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice. EMBO Mol Med. 2009 Apr;1(1):50-65
All:	4 reference(s)