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Tgfb3tm1Moaz
Targeted Allele Detail
Summary
Symbol: Tgfb3tm1Moaz
Name: transforming growth factor, beta 3; targeted mutation 1, Mohamad Azhar
MGI ID: MGI:5313415
Synonyms: Tgfb3cko
Gene: Tgfb3  Location: Chr12:86103519-86125815 bp, - strand  Genetic Position: Chr12, 40.09 cM
Alliance: Tgfb3tm1Moaz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181226
Parent Cell Line:  KG-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site and an FRT flanked MC1-neomycin selection cassette were inserted in intron 5 and a second loxP site was placed in intron 6. (J:181226)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tgfb3 Mutation:  34 strains or lines available
References
Original:  J:181226 Doetschman T, et al., Generation of mice with a conditional allele for the transforming growth factor beta3 gene. Genesis. 2012 Jan;50(1):59-66
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory