Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Atxn2ltm1e(EUCOMM)Hmgu
Name:	ataxin 2-like; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
MGI ID:	MGI:5310993
Gene:	Atxn2l  Location: Chr7:126090880-126102609 bp, - strand  Genetic Position: Chr7, 69.09 cM
IMPC:	Atxn2l gene page

Mutant Cell Lines:	HEPD0684_1_B05, HEPD0684_1_C07, HEPD0684_1_D06, HEPD0684_1_D07, HEPD0684_1_E06, HEPD0684_1_E08, HEPD0684_1_F07, HEPD0684_1_G05, HEPD0684_1_H05, HEPD0684_1_H06
Germline Transmission:	Unknown
Parent Cell Line:	JM8A3.N1 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	EUCOMM

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion     Vector: L1L2_Bact_P   Mutation details: The L1L2_Bact_P cassette was inserted at position 126097105 of Chromosome 7 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157065)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Atxn2l Mutation:	44 strains or lines available

Original:	J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015;
All:	1 reference(s)