Tg(Tagln-Tfpi)1661Rdsi
Transgene Detail
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| Symbol: |
Tg(Tagln-Tfpi)1661Rdsi |
| Name: |
transgene insertion 1661, Robert D Simari |
| MGI ID: |
MGI:5308413 |
| Synonyms: |
SM22alpha-TFPI 1661, SM22a-mTFPI transgenic line 1661 |
| Transgene: |
Tg(Tagln-Tfpi)1661Rdsi Location: unknown
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| Alliance: |
Tg(Tagln-Tfpi)1661Rdsi page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Tagln-Tfpi)1661Rdsi expresses
1 gene
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Mutation details: The transgene was designed with the 441 bp mouse SM22alpha (transgelin; Tagln) promoter fragment upstream of a mouse tissue factor pathway inhibitor (Tfpi) cDNA sequence encoding the TFPIalpha isoform (TFPIalpha is the predominant TFPI protein isoform in humans). Mice with the highest expression of transgenic TFPI mRNA were identified (founder line 1661).
(J:180949)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:180949 Pan S, et al., The effect of vascular smooth muscle cell-targeted expression of tissue factor pathway inhibitor in a murine model of arterial thrombosis. Thromb Haemost. 2004 Sep;92(3):495-502 |
| All: |
3 reference(s) |
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Analysis Tools
