Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Atxn1ltm2.1Hzo
Name:	ataxin 1-like; targeted mutation 2.1, Huda Y Zoghbi
MGI ID:	MGI:5301616
Gene:	Atxn1l  Location: Chr8:110453083-110464371 bp, - strand  Genetic Position: Chr8, 57.22 cM
Alliance:	Atxn1ltm2.1Hzo page

Germline Transmission:	Earliest citation of germline transmission: J:178303
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of the open reading frame and a floxed neo cassette was inserted downstream of the open reading frame via homologous recombination. Cre mediated recombination removed the open reading frame and the neo cassette.

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atxn1l Mutation:	24 strains or lines available

Original:	J:178303 Lee Y, et al., ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization. Dev Cell. 2011 Oct 18;21(4):746-57
All:	2 reference(s)