Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Tet2tm1.2Mjxu
Name:	tet methylcytosine dioxygenase 2; targeted mutation 1.2, Mingjiang Xu
MGI ID:	MGI:5301344
Synonyms:	Tet2:nGFP
Gene:	Tet2  Location: Chr3:133169438-133250882 bp, - strand  Genetic Position: Chr3, 61.84 cM
Alliance:	Tet2tm1.2Mjxu page

Germline Transmission:	Earliest citation of germline transmission: J:178415
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: Cre-mediated recombination of Tet2tm1.1Mjxu removed the nuclear lacZ and left the nuclear GFP (H2B-GFP or nGFP) intact. (J:178415)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tet2 Mutation:	778 strains or lines available

Original:	J:178415 Li Z, et al., Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies. Blood. 2011 Oct 27;118(17):4509-18
All:	3 reference(s)