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Gene Expression Data
Assay Details
Assay
Reference: J:168632 Firtina Z, et al., Unfolded Protein Response (UPR) is activated during normal lens development. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):135-43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5301007
Gene symbol: Hspa5
Gene name: heat shock protein 5
Antibody: anti-BiP
Detection system: Secondary antibody
Results
Specimen 1A E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present Regionally restricted 1A E12.5 BiP Expression is in primary lens fiber cells.
TS20: lens vesicle epithelium Present 1A E12.5 BiP

Specimen 1A E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lens fiber Present Regionally restricted 1A E14.5 BiP Expression is elevated at the transition zone compared to the central fibers.
TS22: lens epithelium Present 1A E14.5 BiP

Specimen 1A E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lens fiber Present Regionally restricted 1A E16.5 BiP Expression is mostly confined to the newly forming fiber cells.
TS24: lens epithelium Present 1A E16.5 BiP

Specimen 1B E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lens fiber Strong Regionally restricted 1B E18.5 BiP Expression is high in the newly forming lens fiber cells and a diffuse staining in central lens fiber cells.
TS26: lens epithelium Strong 1B E18.5 BiP

Specimen 1B 3 mo: postnatal month 3 (more )
Structure Level Pattern Image Note
TS28: lens fiber Present Regionally restricted 1B 3 mo BiP Expression is associated with fiber cells that are getting ready to undergo degradation of nuclei and organelles.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory